Have you tried running God of War III on RPCS3? What build did you use? Let me know in the comments below.

Support the developers. Buy a used copy of the game. Creating a personal backup ISO is a technical exercise; downloading one is theft. Don’t kill the messenger—Kratos kills enough gods as it is.

God of War III is one of the most difficult PS3 games to emulate. If your PC isn't a powerhouse, you will get audio crackling and frame dips. Stick to the PS4 remaster ( God of War III Remastered ) if you just want to play.