George O'Malley technically dies in the Season 6 premiere, Episode 1, titled " Good Mourning
The decision to kill off such a beloved character was fueled by both creative and behind-the-scenes factors: T.R. Knight (George O'Malley) left why?! : r/greysanatomy when does george die in grey's
He is rushed to Seattle Grace Hospital as an unrecognizable "John Doe" because the accident left him severely disfigured. The doctors only realize his identity when he uses his finger to trace —his old intern nickname—into Meredith Grey’s palm. Despite emergency surgery to repair his injuries, George is declared brain dead in the Season 6 premiere due to massive brain swelling. Why Was George Killed Off? George O'Malley technically dies in the Season 6
If you are looking for the specific episode, The doctors only realize his identity when he
George cannot speak, but he manages to use his finger to trace “007” on Dr. Meredith Grey’s palm. “007” was George’s nickname because he always “failed his missions” (like failing his intern exam), referencing James Bond’s license to kill — except for George, it meant he was the one who always got hurt or messed up.